文森特（罗伯特·席安 Robert Sheehan 饰）是一名图雷特综合症患者，照顾她的母亲去世之后，文森特那久未谋面的父亲出现，将儿子送往了治疗中心，交给了在那里工作的罗斯医生（凯拉·塞吉维克 Kyra Sedgwick 饰）。 　　在治疗中心内，文森特结识了艾利克斯（戴夫·帕特尔 Dev Patel 饰）和玛丽（佐伊·克拉维兹 Zoe Kravitz 饰），前者患有强迫症，后者则是一名厌食症患者。同为病患，三位青年之间结下了坚实的友谊，某日，他们偷走了罗斯医生的车，驱车前往海边悼念文森特的母亲。发现了文森特一行人的“越狱”行为，罗斯医生和文森特的父亲当即联手，对三名“逃犯”进行“追捕”。The Road Within is about Vincent, a young man suffering from Tourette Syndrome. His mother dies so his estranged father, Robert, is forced to step in. However, Robert's running for political office and doesn't want his son on the campaign trail - so Robert puts Vincent in a clinic that's run by the unconventional Dr. Mia Rose. Once there, Vincent falls in love with an anorexic woman named Marie. Together, they steal Dr. Rose's car, and end up having to kidnap his OCD roommate, Alex, when he threatens to tell on them. With Robert and Dr. Rose in hot pursuit, Vincent, Marie and Alex go on a life changing road trip to deliver the ashes of his mother to the ocean.