凡纳克精神疗养院内的研究人员曾进行秘密的生物试验，该试验造成病患和医护人员接连死亡。最终，该疗养院废弃，多年来荒凉阴森，无人敢近，成为远近闻名的恐怖鬼屋。 　　性格怪异的亿万富翁史蒂芬•普莱斯（Geoffrey Rush杰佛瑞•罗许 饰）决定在凡纳克精神疗养院为妻子艾芙琳（Famke Janssen 芬卡•杰森 饰）举行一场别出心裁的生日派对，他邀请六个人前来，只要他们敢在这幢“鬼屋”中待上一晚，就有机会获得一百万美元的奖金。挑战者慕名前来，却不知真正的恐怖正等待着他们…… 　　本片荣获2000年百视达娱乐奖最佳男配角奖（Taye Diggs）。When an eccentric millionaire offer a group of opposites $1,000,000 to spend the night in a so called "Haunted House" with a murderous past, they figure it is a quick way to get quick money and leave. All of them are sure it is some made up story just to mess with their heads a little and test their courage. But, once they stay in the house they start to think about the mistake they made in coming there when mysterious things start to happen.