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同名的电影很多，但最有名的当属1931版的《科学怪人》，那部电影是恐怖电影的一个经典，但因为年代太久远，所以看过的人不多，包括阿波罗。在脑海中搜罗了一下以《科学怪人》为名的电影，印象最深刻的应该是1994年德尼罗主演的那部，画面很美，很精致，情节也很感人。相比之下，这部2005年版的电影就不可同日而语了，电影以侦破悬疑片的格调开局，完全摒弃了科学怪人的主题本意，而且对狂人医生如何创造生命也没有细致的交代，结尾更是草草收场，狂人医生毫发无损，继续从事着他的崇高事业。
Baron Frankenstein (cousin of the late scientist who created the famous monster) lives in seclusion on his idyllic island retreat off the coast of Botswana. Here is were he decides to invest his enormous wealth into the research of transient algorithms around Africa's sub continent. In doing so he unleashes a deadly virus into the atmosphere that mutates and takes on a pathogen like life of its own as it's sets out to destroy all in its path. All except one thing, the son of Frankenstein's monster! Will it succeed in destroying the retro virus???